The immune response to cancer can deepen and sustain over time

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The immune response evolves and expands over time by constantly recognizing and remembering tumor antigens. This ability—to propagate and perpetuate—suggests the intelligent nature of the immune response.1

The effects of immune activation are not static; instead, they improve and deepen over time.2 The release of new antigens following tumor cell death fuels the cycle, as new tumor-specific T cells are continuously recruited to kill tumor cells.1-4 Over time, as the cycle is repeated, the antitumor immune response continues to broaden.2